In 2003 Recuperat-ion® designed a 5 years long clinical research program, in order to collect present knowledge of water and ionic flow in the locomotor system, as well as to evaluate Recuperat-ion® efficacy and safety in fatigue and pain reduction.
In 2007 the following trials have been finished:
Peripheral fatigue in athletes (2004): Rehydration in long distance athletes. Study of plasma osmolality and muscular bio-energetic effect by nuclear magnetic resonance.
Central fatigue in athletes (2005): Double blind, randomised, controlled Clinical Trial (…) in healthy volunteers exercise.
Muscular fatigue and pain in Fibromyalgia patients (2006): randomised, triple-blind placebo-controlled study to evaluate the clinical efficacy of an oral rehydration solution Recuperat-ion®, as a food supplement. In fibromyalgia patients.
Preliminary phase trials (muscular fatigue and pain in Fibromyalgia patients):
Identification of patients who respond to Recuperat-ion® treatment.
Identification of adequate dosage and treatment length.
Identification of Recuperat-ion® action mechanisms on cellules.
Promoting Research, Recuperat-ion® intends to offer to specialists a science supported option.
On going research 
Identification of patients who respond to Recuperat-ion® treatment.
